Overview
Table of ContentsPart I THE MOLECULAR DESIGN OF LIFE1. Biochemistry: An Evolving Science 2. Protein Composition and Structure3. Exploring Proteins and Proteomes4. DNA, RNA, and the Flow of Genetic Information 5. Exploring Genes and Genomes 6. Exploring Evolution and Bioinformatics 7. Hemoglobin: Portrait of a Protein in Action 8. Enzymes: Basic Concepts and Kinetics 9. Catalytic Strategies 10. Regulatory Strategies 11. Carbohydrates 12. Lipids and Cell Membranes 13. Membrane Channels and Pumps 14. Signal-Transduction PathwaysPart II TRANSDUCING AND STORING ENERGY15. Metabolism: Basic Concepts and Design 16. Glycolysis and Gluconeogenesis 17. The Citric Acid Cycle18. Oxidative Phosphorylation 19. The Light Reactions of Photosynthesis 20. The Calvin Cycle and the Pentose Phosphate Pathway 21. Glycogen Metabolism 22. Fatty Acid Metabolism 23. Protein Turnover and Amino Acid Catabolism Part III SYNTHESIZING THE MOLECULES OF LIFE24. The Biosynthesis of Amino Acids 25. Nucleotide Biosynthesis 26. The Biosynthesis of Membrane Lipids and Steroids27. The Integration of Metabolism28. DNA Replication, Repair, and Recombination29. RNA Synthesis and Processing 30. Protein Synthesis 31. The Control of Gene Expression in Prokaryotes 32. The Control of Gene Expression in Eukaryotes Part IV RESPONDING TO ENVIRONMENTAL CHANGES33. Sensory Systems34. The Immune System35. Molecular Motors 36 Drug Development