Table of Contents
Contributors
Preface
SECTION I: BASIC PRINCIPLES AND CONSIDERATIONS OF RATIONAL CHEMOTHERAPY AND MOLECULAR TARGETED THERAPY
1 Biologic and Pharmacologic Basis of Cancer Chemotherapy
2 Biologic Basis of Molecular Targeted Therapy
3 Systematic Assessment of the Patient With Cancer and Consequences of Treatment
4 Selection of Treatment for the Patient With Cancer
SECTION II: CHEMOTHERAPY AND MOLECULAR TARGETED THERAPY OF HUMAN CANCER
5 Carcinomas of the Head and Neck
6 Carcinoma of the Lung
7 Carcinomas of the Gastrointestinal Tract
8 Carcinomas of the Pancreas, Liver, Gallbladder, and Bile Ducts
9 Carcinoma of the Breast
10 Gynecologic Cancer
11 Urologic and Male Genital Cancers
12 Kidney Cancer
13 Thyroid and Adrenal Carcinomas
14 Melanomas and Other Cutaneous Malignancies
15 Primary and Metastatic Brain Tumors
16 Soft-Tissue Sarcomas
17 Bone Sarcomas
18 Acute Leukemias
19 Chronic Leukemias
20 Myeloproliferative Neoplasms and Myelodysplastic Syndromes
21 Hodgkin Lymphoma
22 Non-Hodgkin Lymphoma
23 Multiple Myeloma, Other Plasma Cell Disorders, and Primary Amyloidosis
24 Metastatic Cancer of Unknown Origin
25 HIV-Associated Malignancies
SECTION III: SUPPORTIVE CARE OF PATIENTS WITH CANCER
26 Side Effects of Chemotherapy and Molecular Targeted Therapy
27 Infections: Etiology, Treatment, and Prevention
28 Transfusion Therapy, Bleeding, and Clotting
29 Oncology Emergencies and Critical Care Issues: Spinal Cord Compression, Cerebral Edema, Superior Vena Cava Syndrome, Anaphylaxis, Respiratory Failure, Tumor Lysis Syndrome, Hypercalcemia, and Bone Metastasis
30 Malignant Pleural, Peritoneal, and Pericardial Effusions and Meningeal Infi ltrates
31 Cancer Pain
32 Emotional and Psychiatric Problems in Patients with Cancer
SECTION IV: CHEMOTHERAPEUTIC AND MOLECULAR TARGETED AGENTS AND THEIR USE
33 Classification, Use, and Toxicity of Clinically Useful Chemotherapy and Molecular Targeted Therapy
Appendix A: Surface Area of Adults from Height and Mass
Appendix B: Surface Area of Children from Height and Mass