1 Principles of pharmacology 3 2 Structure and function of the nervous system 33 3 Chemical signaling by neurotransmitters and hormones 63 4 Methods of research in neurobehavioral pharmacology 89 5 Catecholamines 119 6 Acetylcholine and serotonin 139 7 Glutamate and GABA 163 8 Drug abuse, dependence, and addiction 185 9 Alcohol 215 10 The opiates 245 11 Psychomotor stimulants : cocaine and the amphetamines 275 12 Nicotine and caffeine 303 13 Marijuana and the cannabinoids 327 14 Hallucinogens, PCP, and ketamine 347 15 Inhalants, GHB, and anabolic-androgenic steroids 365 16 Affective disorders 385 17 Anxiety disorders 411 18 Schizophrenia 441